Influenza A subtype cross-protection after immunization of outbred mice with a purified chimeric NS1/HA2 influenza virus protein

Influenza A subtype cross-protection after immunization of outbred mice with a purified chimeric NS1/HA2 influenza virus protein

Source :

• Vaccine [ 0264-410X ] ; 1994.

Descripteurs français

• KwdFr :
  • Animaux, Aérosols, Cytométrie en flux, Femelle, Infections à Orthomyxoviridae (), Lymphocytes T CD4+ (immunologie), Lymphocytes T CD8+ (immunologie), Protéines recombinantes, Protéines virales (immunologie), Réactions croisées (immunologie), Réplication virale (immunologie), Souris, Souris de lignée BALB C, Souris de lignée C57BL, Tests de cytotoxicité immunologique, Tests de neutralisation, Vaccins antigrippaux (immunologie), Vaccins synthétiques (immunologie), Virus de la grippe A (immunologie).
• MESH :
  • immunologie : Lymphocytes T CD4+, Lymphocytes T CD8+, Protéines virales, Réactions croisées, Réplication virale, Vaccins antigrippaux, Vaccins synthétiques, Virus de la grippe A.
  • Animaux, Aérosols, Cytométrie en flux, Femelle, Infections à Orthomyxoviridae, Protéines recombinantes, Souris, Souris de lignée BALB C, Souris de lignée C57BL, Tests de cytotoxicité immunologique, Tests de neutralisation.

English descriptors

• KwdEn :
  • Aerosols, Animals, CD4-Positive T-Lymphocytes (immunology), CD8-Positive T-Lymphocytes (immunology), Chimeric influenza protein, Cross Reactions (immunology), Cytotoxicity Tests, Immunologic, Female, Flow Cytometry, Influenza A virus (immunology), Influenza Vaccines (immunology), Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Neutralization Tests, Orthomyxoviridae Infections (prevention & control), Recombinant Proteins, Vaccines, Synthetic (immunology), Viral Proteins (immunology), Virus Replication (immunology), cross-protection, influenza A subtype.
• MESH :
  • chemical , immunology : Influenza Vaccines, Vaccines, Synthetic, Viral Proteins.
  • immunology : CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cross Reactions, Influenza A virus, Virus Replication.
  • prevention & control : Orthomyxoviridae Infections.
• Teeft :
  • Active immunization, Adoptive transfer, Aerosols, Agents chemother, Alum, Amino acids, Animals, Antibody responses, Antibody treatment, Antigenic, Antigenic drift, Braciale, Cell response, Chimeric, Chimeric protein, Clone, Control mice, Cotton rats, Cumulative mortality rates, Cytotoxic, Cytotoxicity Tests, Immunologic, Effector, Effector cells, Ennis, Experiments mice, Female, Flow Cytometry, Further evaluation, Haplotype dependence, Immune, Immunization, Immunodominant epitope, Immunol, Inbred, Inbred mice, Infection, Influenza, Influenza nucleoprotein, Influenza pneumonia, Influenza vaccines, Influenza virus, Influenza virus challenge, Influenza virus infection, Influenza viruses, Last injection, Ldso, Lethal dose, Lung virus, Lung virus infection, Lymphocyte, Lymphocyte clones, Mabs, Major histocompatibility, Maximal release, Mbawuike, Mdck cells, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Microneutralization test, Mouse, Natl acad, Neutralization Tests, Neutralizing, Neutralizing activity, Neutralizing antibody, Ntab, Nucleoprotein, Outbred, Outbred mice, Outbred swiss, Passive transfer, Peptide, Present results, Present study, Previous studies, Protection rate, Protective efficacy, Protective immunity, Protein, Proteinimmunized mice, Recombinant, Recombinant Proteins, Respiratory syncytial virus, Significant protection, Spleen cells, Splenic lymphocytes, Squirrel monkeys, Stimulator cells, Subunit, Swiss mice, Syncytial virus, Synthetic peptides, Target cells, Tract infection, Unimmunized mice, Unpublished results, Vaccine, Viral, Viral clearance, Virol, Virus, Virus challenge, Virus infection, Virus infections, Virus titres, Vivo depletion.

Abstract

• https://api.istex.fr/ark:/67375/6H6-2QRMW5H6-Q/fulltext.pdf

Affiliations:

• États-Unis
• Pennsylvanie, Texas

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